Ethnicity Variation in the Treatment of Pediatric Lupus Nephritis
نویسندگان
چکیده
منابع مشابه
The prognosis of lupus nephritis in children
Introduction: Lupus nephritis is a systemic disease which affects different organs. The present study was designed to review lupus nephritis, in children its outcome and the related factors. Methods: We reviewed 48 children with lupus nephritis. Clinical and epidemiological features were studied. The patients’ outcomes and related factors were analyzed. Patient and renal survival rate were ca...
متن کاملTreatment of lupus nephritis.
Renal involvement in systemic lupus erythematosus patients is a severe disease manifestation characterized by various clinical and histopathological alterations. The revised International Society of Nephrology/Renal Pathology Society 2003 classification defines the subclasses of lupus nephritis (LN) according to their pathological glomerular patterns, which has a crucial impact on the prognosis...
متن کاملPediatric lupus nephritis: impact of ethnicity on histological subtype and initial presentation
Methods A single-center cohort study of all consecutive patients <18 years of age with biopsy proven LN diagnosed in 1980–2006 was performed. Self-designated ethnicity, clinical and laboratory features including renal function, urinalysis and overall activity (SLEDAI) were recorded. Associations of ethnicities, LN subtypes, clinical and laboratory variables were tested using chi-squared analysi...
متن کاملInfluence of race/ethnicity on response to lupus nephritis treatment: the ALMS study
OBJECTIVE To compare the efficacy and safety of mycophenolate mofetil (MMF) and intravenous cyclophosphamide (IVC) as induction treatment for lupus nephritis (LN), by race, ethnicity and geographical region. METHODS A total of 370 patients with active Class III-V LN received MMF (target dose 3.0 g/day) or IVC (0.5-1.0 g/m(2)/month), plus tapered prednisone, for 24 weeks. Renal function, globa...
متن کاملUpdate on the treatment of lupus nephritis.
Lupus nephritis (LN) is a major cause of morbidity and mortality in patients with systemic lupus erythematosus. Although the use of aggressive immunosuppression has improved both patient and renal survival over the past several decades, the optimal treatment of LN remains challenging. Improved outcomes have come at the expense of significant adverse effects owing to therapy. Moreover with long-...
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ژورنال
عنوان ژورنال: Biomedical Journal of Scientific & Technical Research
سال: 2018
ISSN: 2574-1241
DOI: 10.26717/bjstr.2018.11.002062